Fig. 6
From: hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages
hUC-MSC transplantation alleviated renal function in 14-week-old MRL/lpr mice. A The 24 h urinary protein (a) and albumin/creatinine ratio (ACR) (b) in the middle-dose hUC-MSC transplantation (MD) showed a significant decrease compared to the control (Ctrl). B The plasma levels of creatinine (a) and blood urea nitrogen (BUN) (b) in the MD and HD groups were significantly decreased compared to the Ctrl, and the plasma levels of complement 3 (C3) (c) in LD and MD groups was significantly increased compared to the Ctrl. C The plasma level of albumin/globulin (A/G) (a) and glycocholic acid (CG) (b) in the high-dose hUC-MSC transplantation (HD) group increased compared to the Ctrl, the plasma levels of triglyceride (TG) (c) and total bile acid (TBA) (d) in the MD group showed a reduction, and hUC-MSC transplantation significantly decreased the plasma levels of inorganic phosphorus (P) (e) and Uric Acid (UA) (f). *P < 0.05; **P < 0.01, ***P < 0.001. (Ctrl: control, LD: low dose, MD: middle dose, HD: high dose). The number of mice is n = 5