Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Physiological oxygen conditions enhance the angiogenic properties of extracellular vesicles from human mesenchymal stem cells

Fig. 5

Effect of EVs isolated from MSCs cultured in normoxic (18.4% O2) and physioxic (3% O2) conditions on CMEC angiogenic and tight junction gene expression. Fold change in gene expression of ANG1, FGF2, HIF1, TGFB1, VEGF, claudin-5 (CLDN5), OCLN, and TJP1 normalized to 18S for CMECs exposed to EGM-2 or 20× EV conditions compared to control EBM-2. Statistical significance shown in comparison to control. N = 5, *P < 0.05, **P < 0.01, bars represent mean and SD

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512