Fig. 4
From: Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells
Protein secretion profile of hBM-MSCs cultured in topographical substrates. A Venn diagrams of differentially expressed proteins (fold change > 2 relative to TCP) of hBM-MCS from four different donors cultured in grooves, anisotropic roughness and spiral micropatterns. B GO top 20 enriched bioprocesses of hBM-MSCs cultured in grooves, anisotropic roughness and spiral micropatterns revealing enhancement in pathways related to immune regulation (adj. p < 0.01). C GO top 20 enriched bioprocesses of donors 182, 271, 263 and 267 (left to right) cultured in grooved surfaces (adj. p < 0.01). D Differentially upregulated (green) and downregulated (red) secreted proteins of donors 182, 271, 263 and 267 (left to right) cultured in grooved surfaces. Data depicts the log2 fold change (relative to the TCP control)