Fig. 5
From: Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells
YAP/TAZ levels in hBM-MSCs cultured in topographical substrates. A Representative immunofluorescence images of hBM-MSCs donor 182 showing distinct distributions of YAP/TAZ (green) in the topographical surfaces. Scale bar = 100 µm. B–C Image-based analysis of YAP/TAZ expression levels in hBM-MSCs donors 182 and 271 cultured on each substrate. Data show the average total (B) and nuclear (C) levels for each donor. Error bars depict the mean ± SEM of 2 independent experiments with n = 27–65 quantified cells. Asterisk (*) represent p-values < 0.05, (**) p-values < 0.01, (***) p-values < 0.001 and (****) p-values < 0.0001