Table 1 Baseline patient demographic and clinical characteristics
Characteristics | Invimestrocel group (N = 20) | Standard group (N = 10) |
|---|---|---|
Age at informed consent obtained (years) | ||
Mean (SD) | 69.2 (13.2) | 66.5 (10.8) |
Median | 70.5 | 67.0 |
Min–max | 44–89 | 48–85 |
Age category, n (%) | ||
< 75 years | 13 (65) | 7 (70) |
≥ 75 years | 7 (35) | 3 (30) |
Sex, n (%) | ||
Male | 16 (80) | 10 (100) |
Female | 4 (20) | 0 |
Smoking status, n (%) | ||
Current | 5 (25) | 3 (30) |
Former | 9 (45) | 5 (50) |
Never | 6 (30) | 1 (10) |
Missing, n | 0 | 1 |
Alcohol consumption, n (%) | ||
Current | 10 (50) | 4 (40) |
Former | 8 (40) | 4 (40) |
Never | 2 (10) | 1 (10) |
Missing, n | 0 | 1 |
PaO2/FIO2 ratio at diagnosis (mmHg) | ||
Mean (SD) | 125.7 (52.3) | 151.3 (62.7) |
Median (IQR) | 117.1 (95.3–149.0) | 128.0 (104.4–186.3) |
PaO2/FIO2 ratio category, n (%) | ||
≤ 100 mmHg | 6 (30) | 2 (20) |
100 mmHg to ≤ 200 mmHg | 13 (65) | 6 (60) |
200 mmHg to ≤ 300 mmHg | 1 (5) | 2 (20) |
Estimated HRCT score at screening (Evaluator 1) | ||
n | 20 | 10 |
Mean (SD) | 237.5 (43.0) | 241.0 (35.7) |
Median (IQR) | 230.0 (210.0–270.0) | 250.0 (210.0–270.0) |
APACHE II score | ||
Mean (SD) | 19.8 (5.1) | 19.6 (3.0) |
Median (IQR) | 20.5 (17.0–24.0) | 20.0 (18.0–21.0) |