Fig. 2

Schematic diagram of the effects of intracellular signaling pathways associated with Piezo channels on MSCs. Piezo channels are activated by mechanical stimulation, which causes the influx of Ca²⁺ into the cells and leads to the activation of multiple intracellular signaling pathways, producing a cascade of signals and ultimately regulating the functions of MSCs. This figure was created for this article, and the image depicted in this figure is ours; it is not based on any previously published image