Table 1 Basic clinical data of healthy people, CHB patients and ACLF patients
Groups | Normal people (n = 27) | CHB patients (n = 52) | ACLF patients (n = 145) | P value |
|---|---|---|---|---|
Age (years) | 35 ± 15 | 38 ± 11 | 48 ± 12 | 0.095 |
Sex, male /female | 19/8 | 38/14 | 116/29 | 0.085 |
INR | 0.97 ± 0.09 | 1.15 ± 0.16 | 2.19 ± 0.79 | < 0.001 |
TBiL (μmol/L) | 9.48(5.95–12.45) | 145.89(42.4–222) | 406.74(281.8–508.5) | < 0.001 |
ALT (IU/L) | 21(16–36) | 220(90–856) | 99(51–262) | 0.001 |
ALB(g/L) | 46.73 ± 4.51 | 36.98 ± 4.8 | 31.96 ± 3.46 | < 0.001 |
Cr (μmol/L) | 74.14 ± 24.14 | 71.83 ± 12.43 | 87.88 ± 24.41 | 0.104 |
WBC(× 109/L) | 6.99 ± 2.45 | 5.44 ± 1.69 | 7.12 ± 3.84 | 0.093 |
PLT(× 109/L) | 195.6(119.5–245) | 176.52(126–232) | 95.23(58–126) | < 0.001 |
AFP(ng/ml) | 2.95(2.5–6) | 39.42(4.74–116.69) | 54.67(13.25–254.78) | < 0.001 |