Fig. 5

OM-MSCs recruit Treg cells and inhibit the inflammation. A–D qRT-PCR evaluates expressions of Il1b, Il6, Tnf, Il10 of brain tissue from Vehicle, Vehicle + OM-MSCs, Pilo, and Pilo + OM-MSCs group. n = 18 per group. E–G ELISA analysis of protein level of IL1B, IL6, and TNF from brain of each indicated group. n = 5 per group. H–K Representative images and quantification of immunofluorescent staining of double-positive CD4⁺CD25⁺ and CD4⁺FOXP3⁺ cells (Treg cells) from brains of Vehicle, Vehicle + OM-MSCs, Pilo, and Pilo + OM-MSCs group. n = 5 per group for CD4⁺CD25⁺ cells and n = 11 per group for CD4⁺FOXP3⁺ cells