Fig. 2

SVZ neurogenesis in adult Seipin KO mice. A–C Immunofluorescence analysis for Ki67, DCX, and BrdU/NeuN in SVZ (A and B) and olfactory bulb (C) of juvenile and adult WT and Seipin KO mice, respectively. The right panel corresponded to a higher magnification view of the boxed region shown in the merged image. n = 6 (A and B), Scale bar = 50 μm in (A), Scale bar = 25 μm in (B); n = 4, Scale bar = 200 μm in (C). D and E The proliferation and differentiation capacity of cells as determined by BrdU staining and Tuj1 staining in NSCs from neonatal (D) and adult mice (E), respectively. DAPI was used as a nuclear counterstain. Scale bar = 50 μm in (D and E). Data were shown as means ± SD. *p < 0.05 vs. adult WT