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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Adipose transplantation improves olfactory function and neurogenesis via PKCα-involved lipid metabolism in Seipin Knockout mice

Fig. 5

SVZ neurogenesis and neurological function in adult Seipin KO mice after AT transplantation. AC Immunofluorescence staining and analysis of Ki67 (A), DCX (B), and BrdU+/NeuN+ (C) in the SVZ and olfactory bulb granular layer of each group to show neurogenesis of adult Seipin KO mice. n = 5, Scale bar = 50 μm in (A and B); n = 3, Scale bar = 50 μm in (C). *p < 0.05 vs. WT-Sham, #p < 0.05 vs. KO-Sham. D Olfactory habituation/dishabituation assay of Seipin KO and WT mice with or without AT transplantation (n = 5). E Short-term olfactory memory test Seipin KO mice before with or without AT transplantation (n = 5). *p < 0.05 vs.1st. F Odor avoidance tests in the presence of different doses of nTMT in Seipin KO mice before with or without AT transplantation (n = 5). *p < 0.05 vs. WT-Sham, #p < 0.05vs. KO-Sham. Data were shown as means ± SD

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