Table 1 Components of HSC niche
Cellular components | Extracellular matrix | Biophysical parameters |
|---|---|---|
Mesenchymal stem cells | Polysaccharide | Shear stress |
Osteolineage cells | Proteoglycans | Hydrostatic pressure |
Adipocytes | Collagens | Circumferential strain |
Endothelial cell | Laminins | Stiffness |
Sympathetic nerves | Fibronectin | Viscoelasticity |
Schwann cells | Osteopontin | 3D architecture |
Macrophages | Â | Nanotopography |
T cells | Â | Â |
Neutrophils | Â | Â |