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Table 3 Comparison of mfERG amplitudes of P1 waves at baseline and final examination (6th months) (n = 11)

From: Suprachoroidal spheroidal mesenchymal stem cell implantation in retinitis pigmentosa: clinical results of 6 months follow-up

 

Ring

Amplitude of P1 wave (nV)

p*

Preop

Postop. 6th months

 < 2°

Treated eye

Median (IQR)

362.0 (159.0–612.0)

672.0 (564.0–1013.0)

0.014

Mean ± SD

412.7 ± 291.7

830.3 ± 497.9

Fellow eye

Median (IQR)

352.0 (163.0–600.0)

268.0 (225.0–564.0)

0.509

Mean ± SD

399.1 ± 254.0

347.7 ± 174.9

p

 

0.909**

0.001***

 

2°–5°

Treated eye

Median (IQR)

227.0 (180.0–297.0)

217.0 (167.0–446.0)

0.101

Mean ± SD

215.2 ± 86.7

299.0 ± 174.2

Fellow eye

Median (IQR)

180.0 (100.0–250.0)

200.0 (95.0–386.0)

0.406

Mean ± SD

219.0 ± 175.0

255.3 ± 195.5

p

 

0.365***

0.562***

 

5°–10°

Treated eye

Median (IQR)

163.0 (111.0–231.0)

282.0 (127.0–313.0)

0.018

Mean ± SD

175.4 ± 86.4

248.3 ± 108.5

Fellow eye

Median (IQR)

121.0 (75.0–131.0)

103.0 (94.0–198.0)

0.834

Mean ± SD

129.0 ± 68.5

134.0 ± 75.2

p

 

0.133***

0.009**

 

10°–15°

Treated eye

Median (IQR)

161.0 (92.2–170.0)

269.0 (174.0–295.0)

0.017

 

Mean ± SD

147.4 ± 65.8

267.4 ± 139.5

Fellow eye

Median (IQR)

164.0 (99.0–198.0)

120.0 (72.4–240.0)

0.883

Mean ± SD

154.3 ± 62.0

149.6 ± 85.7

p

 

0.802**

0.027**

 

> 15°

Treated eye

Median (IQR)

83.2 (53.1–183.0)

164.0 (91.0–210.0)

0.152

Mean ± SD

117.2 ± 78.3

152.3 ± 69.5

Fellow eye

Median (IQR)

77.4 (57.0–97.2)

100.0 (60.0–112.0)

0.053

Mean ± SD

73.2 ± 26.1

98.3 ± 43.4

p

 

0.102**

0.088***

 
  1. mfERG multifocal electroretinogram, SD standard deviation and IQR interquartile range
  2. *Paired samples t-test
  3. **Independent samples t-test
  4. ***Mann–Whitney U-test
  5. Bold face values represent statistical significance