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Table 4 Comparison of mfERG implicit times of P1 waves at baseline and final examination (6th month) (n = 11)

From: Suprachoroidal spheroidal mesenchymal stem cell implantation in retinitis pigmentosa: clinical results of 6 months follow-up

 

Ring

Implicit time of P1 wave (ms)

p*

Preop

Postop. 6th months

 < 2°

Treated eye

Median (IQR)

51.9 (49.6–55.8)

41.4 (36.1–57.8)

0.163

Mean ± SD

51.4 ± 9.34

44.8 ± 11.6

Fellow eye

Median (IQR)

52.9 (38.1–64.3)

43.7 (34.4–65.1)

0.754

Mean ± SD

51.3 ± 14.4

49.5 ± 16.6

p

 

0.989**

0.0453**

 

2°–5°

Treated eye

Median (IQR)

53.6 (43.6–58.2)

43.1 (34.7–46.6)

0.073

 

Mean ± SD

51.1 ± 10.3

43.9 ± 9.5

Fellow eye

Median (IQR)

42.2 (40.6–44.6)

44.3 (32.4–65.5)

0.645

Mean ± SD

44.1 ± 8.9

46.1 ± 15.9

p

 

0.065***

0.700**

 

5°–10°

Treated eye

Median (IQR)

43.3 (37.9–61.3)

42.2 (32.3–54.6)

0.572

Mean ± SD

49.9 ± 14.3

46.6 ± 14.8a

Fellow eye

Median (IQR)

53.9 (42.2–69.0)

70.0 (47.7–72.3)

0.281

Mean ± SD

53.8 ± 14.4

60.6 ± 17.1

p

 

0.531**

0.088***

 

10°–15°

Treated eye

Median (IQR)

65.2 (47.2–70.0)

49.6 (35.6–59.5)

0.004

Mean ± SD

59.2 ± 13.6

47.2 ± 12.2

Fellow eye

Median (IQR)

47.2 (64.3–67.7)

60.0 (40.4–67.9)

0.120

Mean ± SD

50.5 ± 16.4

57.7 ± 14.9

p

 

0.192**

0.087**

 

> 15°

Treated eye

Median (IQR)

52.3 (53.1–183.0)

57.3 (43.2–67.5)

0.515

Mean ± SD

51.0 ± 10.3

54.6 ± 13.2

Fellow eye

Median (IQR)

52.3 (40.8–63.2)

53.6 (40.0–65.0)

0.952

Mean ± SD

53.4 ± 11.3

53.1 ± 16.6

p

 

0.605**

0.819**

 
  1. mfERG multifocal electroretinogram, SD standard deviation and IQR interquartile range
  2. *Paired samples t-test
  3. **Independent samples t-test
  4. ***Mann–Whitney U-test
  5. Bold face value represents statistically significant improvement in implicit time of P1 waves in 10°–15° rings postoperatively