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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway

Fig. 4

Transcriptional profiling of ADPRHL1-deficient CMs. A Analysis of significant differential genes of WT-CMs and KO-CMs at day 20 (FDR < 0.001, log2FC ± 1). B Volcano plot showed the distribution of differential genes of WT-CMs and KO-CMs at day 20. C Gene clustering by Z score using Euclidean distance metric in WT-CMs and KO-CMs at day 20. D Enriched KEGG pathway analysis showed the significantly enriched pathways of WT-CMs and KO-CMs at day 20. E GO analysis showed the DEGs of WT-CMs and KO-CMs at day 20 were enriched in cellular components, molecular function and biological processes

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