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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models

Fig. 6

a An inflammatory phenotype was elicited in THP-1 monocytes by treating for 1 h with LPS. This could be measured by TNF-α release measured by Lumit assay, which persisted at least 19 h following LPS withdrawal. b MetRSL274G-expressing iMSCs were cultured with naïve or LPS-treated THP-1 cells. Conditioned media were evaluated using L507 antibody array to identify differently secreted iMSC-proteins. c 15 proteins were differentially secreted from iMSCs cultured with LPS-treated vs naïve THP-1 cells in 3 biological replicates

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Stem Cell Research & Therapy

ISSN: 1757-6512