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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Fig. 4

iCMPs differentiate into sarcomere-forming CM-like cells. a Schematic outline of the protocol used to differentiate iCMPs into CMs. b Immunofluorescent staining for cardiovascular lineage markers (magenta) in combination with eGFP (cyan) in iCMPs 20 days after differentiation initiation. iCMPs differentiate into CM as indicated by sarcomere-like striations in cells labeled by cTnT, α-actinin, and myosin. Neither CD31-positive cells nor an increase in number or fluorescence intensity of alpha smooth muscle actin (α-SMA)-positive cells are evident. DAPI (yellow) marks cell nuclei. Scale bars, 100 µm Figure 5

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Stem Cell Research & Therapy

ISSN: 1757-6512