Fig. 2
From: Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics
Sources of SCs, novel treatments using SCs and potential mechanisms of SC-based therapy in PF. There are many different sources of SCs, such as bone marrow, adipose tissue, umbilical cord, PDS, urine and amniotic fluid. Pretreatment and genetic modification can also be used to enhance the effects of SCs. SCs act through multiple mechanisms, including by affecting the differentiation of MCs, exerting paracrine effects and regulating inflammatory responses. MMT mesothelial–mesenchymal transition. Created with BioRender.com