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Table 2 Major cytokines produced by stem cells and their receptors

From: Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics

Cytokine

Secretory cell

Cytokine receptor

Receptor cell

TSG-6

MSCs [87, 90],

AFSCs [50, 89]

CD44 [90]

Macrophages

HGF

AD-MSCs [35]

c-Met [91]

Mesothelial cells

IL-6

AD-MSCs [43],

BM-MSCs [40]

IL-6R [40]

Macrophages

PGE2

MSCs [92]

EP2, EP4 [93]

Macrophages

USCs [49]

–

CD4 + T cells

IDO

BM-MSCs [41]

–

–

TGF-β

MSCs [94]

TGF-βR

Macrophages

  1. A brief list of the major cytokines secreted by stem cells in attenuating peritoneal fibrosis and the corresponding receptors and receptor cells
  2. SCs stem cells, MSCs mesenchymal stem cells, TSG-6 tumour necrosis factor-α-induced protein 6, AD-MSCs adipose-derived MSCs, AFSCs amniotic fluid SCs, HGF hepatocyte growth factor, c-Met cellular mesenchymal–epithelial transition factor, BM-MSCs bone marrow MSCs, PGE2 prostaglandin E2, EP2 prostaglandin E2 receptor 2, EP4 prostaglandin E2 receptor 4, USCs urine-derived SCs, IDO indoleamine 2,3-dioxygenase