Cytokine | Secretory cell | Cytokine receptor | Receptor cell |
---|
TSG-6 | MSCs [87, 90], AFSCs [50, 89] | CD44 [90] | Macrophages |
HGF | AD-MSCs [35] | c-Met [91] | Mesothelial cells |
IL-6 | AD-MSCs [43], BM-MSCs [40] | IL-6R [40] | Macrophages |
PGE2 | MSCs [92] | EP2, EP4 [93] | Macrophages |
USCs [49] | – | CD4 + T cells |
IDO | BM-MSCs [41] | – | – |
TGF-β | MSCs [94] | TGF-βR | Macrophages |
- A brief list of the major cytokines secreted by stem cells in attenuating peritoneal fibrosis and the corresponding receptors and receptor cells
- SCs stem cells, MSCs mesenchymal stem cells, TSG-6 tumour necrosis factor-α-induced protein 6, AD-MSCs adipose-derived MSCs, AFSCs amniotic fluid SCs, HGF hepatocyte growth factor, c-Met cellular mesenchymal–epithelial transition factor, BM-MSCs bone marrow MSCs, PGE2 prostaglandin E2, EP2 prostaglandin E2 receptor 2, EP4 prostaglandin E2 receptor 4, USCs urine-derived SCs, IDO indoleamine 2,3-dioxygenase