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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Exosomes derived from mesenchymal stem cells primed with disease-condition-serum improved therapeutic efficacy in a mouse rheumatoid arthritis model via enhanced TGF-β1 production

Fig. 5

Flow-cytometric determination of T cell subsets, CD138 cells, macrophage subset, and the T helper cell subset in the spleen taken from the experimental groups. A CD4+T cells: CD8+T cells; B CD138+ cells; C CD64+ cells of CD45+ cells; D CD11c-CD206+ (M2) cells of CD45+CD64+ cells; E M1 (CD45+CD64+CD11c+CD206−) cells; F Treg (CD4+CD25+Foxp3+) cells; G Th17 (CD4+CD25+ROR-γt+) cells; H Treg:Th17 I Th1 (CD4+CD25+T-bet+) cells; J Th2 (CD4+CD25+GATA3+) cells; (K) Th1:Th2. Data obtained from experimental groups were compared using one-way analysis of variance followed by Tukey’s multiple comparison post-hoc tests (n = 6/group). *, Significant (p < 0.05) differences from the control (C group)

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Stem Cell Research & Therapy

ISSN: 1757-6512