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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair

Fig. 8

Skin wound repair potential of construct 1 and hADM in an in vivo model. Macroscopic appearance of the wounds at 8 and 30 days after treatment: hADM (A and B), construct 1 (E and F), untreated wound (I and J), normal skin (M). Representative images of histological sections of repaired wounds at day 30 using hADM (C and D), construct 1 (G and H), untreated wound (K and L), and normal skin (N and O). Hematoxylin & eosin (C, G, K, N) and Masson trichrome stain (D, H, I, O). Wound closure rate (P). SE: stratified epithelium, BM: basement membrane, DP dermal papillae, D Dermis, COL collagen fibers. Scale bar = 200 μm. n = 6. p < 0.01(**)

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Stem Cell Research & Therapy

ISSN: 1757-6512