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Table 1 Histological evaluation of wounds

From: Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair

 

hADM

Construct 1

Untreated wound

Epithelialization

Stratum Basale

+++

+++

−

Stratum Spinosum

+++

+++

−

Stratum Granulosum

+++

+++

−

Stratum Lucidum

+++

+++

−

Stratum Corneum

+++

+++

−

Collagen fibers

Thick fibers

++

+++

−

Thin fibers

+++

++

+++

  1. Histological evaluation for hADM, Construct 1 and Untreated wound. Criteria for estimation of epithelialization and collagen fibers thickness from biopsy samples: (−: none, + : mild, ++ : moderate, +++ : marked). n = 6