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Table 1 Baseline characteristics of the patients treated with UCBT (n = 80)

From: A predictive model combining clinical characteristics and nutritional risk factors for overall survival after umbilical cord blood transplantation

Characteristic

 

Age, median (range)

31 (17, 61)

Sex, n (%)

 Female

37 (46.3)

 Male

43 (53.7)

Diagnosis, n (%)

 AML

35 (43.8)

 ALL

20 (25.0)

 AA

13 (16.2)

 MDS

8 (10.0)

 Other

4 (5.0)

Disease status prior to transplantation, n (%)

 PR/NR

25 (31.3)

 CR

55 (68.7)

HLA compatibility (/10), n (%)

 ≤ 6

25 (31.3)

 7–8

44 (55.0)

 ≥ 9

11 (13.7)

Conditioning regimen, n (%)

 RIC

11 (13.8)

 MAC

69 (86.2)

ABO incompatibility, n (%)

 Identical

29 (36.3)

 Major

17 (21.3)

 Minor

23 (28.7)

 Bidirectional

11 (13.7)

 Infused TNC, (mean ± SD) × 107/kg

2.79 ± 3.35

 Infused CD34+cells, (mean ± SD) × 105/kg

1.81 ± 1.24

aGvHD, n (%)

 Grade 0–I

48 (60.0)

 Grade II–IV

32 (40.0)

CMV infection posttransplant, n (%)

 With

61 (76.3)

 Without

19 (23.7)

Pulmonary infection posttransplant, n (%)

 With

21 (26.3)

 Without

59 (73.7)

PES, n (%)

 With

51 (63.7)

 Without

29 (36.3)

  1. OS overall survival, DFS disease-free survival, UCBT umbilical cord blood transplantation, HR hazard ratio, CI confidence interval, AML acute myeloid leukemia, ALL acute lymphoblastic leukemia, AA aplastic anemia, MDS myelodysplastic syndrome, PR partial remission, NR nonremission, CR complete remission, HLA human leukocyte antigen, RIC reduced intensity conditioning, MAC myeloablative conditioning, TNC total nucleated cell, aGvHD acute graft-versus-host disease, CMV cytomegalovirus, PES pre-engraftment syndrome