Table 3 Univariate and multivariate analysis of OS in 80 patients treated with UCBT

Age

1.021

0.976–1.067

0.369

1.006

0.966–1.047

0.782

Sex, female vs. male

0.570

0.195–1.668

0.305

1.199

0.499–2.883

0.685

Diagnosis

 AML

0.247

0.535

0.655

 ALL

1.480

0.330–6.643

0.609

2.895

0.545–15.383

0.212

1.473

0.464–4.672

0.511

 AA

4.373

1.169–16.359

0.028

0.389

0.026–5.903

0.496

2.501

0.791–7.907

0.118

 MDS

2.759

0.503–15.135

0.242

0.904

0.122–6.728

0.922

1.553

0.322–7.497

0.584

 Other

2.685

0.298–24.187

0.379

0.083

0–31.607

0.412

1.537

0.188–12.553

0.688

Disease status prior to transplantation

 PR/NR vs. CR

3.610

1.283–10.157

0.015

7.948

1.405–44.963

0.019

2.635

1.095–6.342

0.031

2.408

0.860–6.741

0.094

HLA compatibility (/10)

 ≤ 6

0.962

0.834

 7–8

0.855

0.280–2.615

0.784

1.332

0.469–3.782

0.590

 ≥ 9

0.934

0.181–4.289

0.935

1.451

0.346–6.093

0.611

Conditioning regimen

 RIC vs. MAC

3.971

1.351–11.672

0.012

12.707

1.041–155.049

0.046

2.665

0.965–7.355

0.058

3.186

0.874–11.616

0.079

ABO incompatibility

 Identical

0.821

0.251

 Major

1.544

0.471–5.064

0.473

1.981

0.742–5.288

0.172

 Minor

0.842

0.237–2.982

0.789

0.610

0.184–2.028

0.420

 Bidirectional

0.000

0-NA

0.978

0.000

0-NA

0.976

Infused TNC, × 10⁷/kg

1.077

0.997–1.163

0.058

1.219

0.975–1.524

0.082

1.070

0.990–1.156

0.086

1.071

0.983–1.168

0.117

Infused CD34⁺cells, × 10⁵/kg

1.046

0.705–1.551

0.824

1.002

0.697–1.443

0.990

aGvHD, grade II-IV vs. 0-I

1.919

0.695–5.299

0.208

1.351

0.559–3.262

0.504

CMV, with vs. without

0.880

0.280–2.765

0.827

1.298

0.434–3.884

0.641

Pulmonary infection, with vs. without

1.521

0.520–4.453

0.444

1.353

0.519–3.523

0.536

PES, with vs. without

1.227

0.419–3.591

0.709

0.730

0.303–1.763

0.485

BMI before transplant

 Underweight

0.668

0.589

 Normal

2.453

0.317–18.999

0.390

0.636

0.145–2.781

0.548

 Overweight

1.917

0.199–18.430

0.573

0.562

0.162–1.942

0.362

BMI at + 30d posttransplant

Overweight vs. normal/underweight

1.163

0.262–5.157

0.843

0.810

0.188–3.493

0.777

Ratio of BMI change, reduced ≥ 8% vs. increased/reduced < 8%

2.335

0.798–6.836

0.122

1.400

0.580–3.380

0.454

Calf skinfold thickness

 ≥ 20.5 mm vs. < 20.5 mm

3.155

1.050–9.479

0.041

6.940

1.699–28.345

0.007

2.691

1.016–7.128

0.046

3.485

1.180–10.289

0.024

Calf circumference, cm

1.014

0.918–1.119

0.790

1.012

0.930–1.100

0.785

Hand grip

0.969

0.917–1.024

0.265

0.968

0.923–1.015

0.175

Albumin, < 33.6 g/L vs. ≥ 33.6 g/L

6.756

1.524–29.952

0.012

44.701

3.443–580.360

0.004

3.196

1.161–8.798

0.025

5.612

1.705–18.474

0.005

PG-SGA

 A

0.778

0.339

 B

6052.070

0–3.396E + 176

0.966

0.194

0.022–1.743

0.143

 C

9644.803

0–5.406E + 176

0.964

0.292

0.038–2.242

0.236

ESCA, ≥ 122.5 vs. < 122.5

2.737

0.800–9.361

0.109

1.528

0.493–4.739

0.463

GSES

1.014

0.949–1.083

0.687

0.997

0.940–1.058

0.928

EORTC-QLQ-C30, ≥ 59.5 vs. < 59.5

33.388

0.091–12199.203

0.244

2.480

0.558–11.020

0.233

FACT-BMT, ≥ 81 vs. < 81

1.105

0.296–4.119

0.882

1.144

0.396–3.306

0.804