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Table 3 Main characteristics of cell preparation and the cellular product applied

From: Autologous mesenchymal stromal cells embedded with Tissucol Duo® for prevention of air leak after anatomical lung resection: results of a prospective phase I/II clinical trial with long-term follow-up

Case number

Amount of bone marrow obtained (mL)

Complications during bone marrow harvest

Number of MSC obtained after expansion

Number of MSC applied in suture line

Surgical procedure

Surgical approach

Complications during treatment

1

90

No

60 million

60 million

Left upper lobectomy

Thoracotomy

No

2

90

No

104 million

60 million

Segmentectomy (Left S1-3)

Thoracotomy

No

3

82

No

142 million

36 million

Middle lobectomy

VATS

No

4

95

No

255 million

60 million

Right upper lobectomy

VATS

No

5

90

No

Insufficient expansion

Not applied

Segmentectomy (Left S1-3 and S6)

Thoracotomy

6

80

No

120 million

60 million

Left upper lobectomy

VATS

No

7

90

No

100 million

60 million

Right upper lobectomy + wedge middle lobe + wedge S6

VATS

No

8

90

No

45 million

35 million

Wedge right upper lobe + wedge middle lobe + mechanical and chemical pleurodesis

VATS

No

  1. VATS video-assisted thoracic surgery