Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential

Fig. 4

Detection of mutation through PCR amplification and Sanger sequencing of control, healthy BJ-hiPSC and diseased SBG1, 2, 3, 5-iPSC. Following extraction of mtDNA, detection of mutation through PCR amplification and Sanger sequencing of mtDNA was conducted in a SBG1-hiPSC (8993 T > G) b SBG2-hiPSC (8993 T > G) c SBG3-hiPSC (9185T > C) and (d) SBG5-hiPSC (12706 T > C). mtDNA, mitochondrial DNA. Mutation was detected in all diseased hiPSCs while absent in the control, healthy BJ-hiPSCs

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512