Fig. 6

Glycolytic profile of hiPSC lines. a a scheme shows the glycolytic acidification, b PER of BJ-iPSC and diseased (SBG1, 2, 3, 5) hiPSCs, c basal glycolysis, d compensatory glycolysis after ETC blocking using Rot/AA, e total proton efflux rate, f post-2-DG (non-glycolytic acidification). Data are shown in pmol H + /min/1000 cells as mean ± SD. Experiments were repeated at least three times on different days under the same conditions. *p < 0.05**p < 0.01***p < 0.001****p < 0.00001. Comparative analyses for all diseased (SBG1, 2, 3, 5) hiPSCs were conducted with the healthy control BJ-hiPSC line. PER: proton efflux rate