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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential

Fig. 8

SBG5-hiPSCs differentiation into cardiomyocytes (CMs). Representative fluorescent images of positive immunocytochemistry stain of cardiac markers such as α-sarcomeric actinin (green) and cardiotroponin T (red) a BJ-hiPSC-CMs and (b) SBG5-hiPSC-CMs. Nucleus was counterstained with Nucblue (blue), and overlaid images were created. c A graph figure of beating frequency calculated by counting beats per minute in SBG5-hiPS-CMs in comparison to control BJ-hiPSC-CMs. ****p < 0.0001. Scale bar = 100 µm

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Stem Cell Research & Therapy

ISSN: 1757-6512