Fig. 3

sFgl2-MSCs significantly alleviate liver injury in AIH mice. A Live organ imaging confirming that MSCs can reach the liver. B H&E staining showing pathological injuries in each group (20 ×). The black arrows show the positive staining areas. C Data display of liver necrosis area in each group, n = 6. D Liver damage was quantified in each group according to the Knodell scoring system, n = 6. E Serum AST levels in each group were determined by ELISA, n = 6. F Serum ALT levels in each group were determined by ELISA, n = 6. The differences between groups were calculated using ANOVA. ***: P < 0.001. Abbreviations: MSCs, mesenchymal stem cells; sFgl2, soluble fibronectin-like protein 2; WT-MSCs, wild-type MSCs; NC-MSCs, negative control MSCs; ALT, alanine transaminase; AST: aspartate transaminase