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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: sFgl2 gene-modified MSCs regulate the differentiation of CD4+ T cells in the treatment of autoimmune hepatitis

Fig. 5

sFgl2-MSCs reduced the proportions of CD4+ T cells and CD8+ T cells in the spleen and liver in experimental AIH mice. A Dot plots showing CD4+ T cells in the spleen and liver. B The proportions of CD4+ T cells in the spleen in the different groups, n = 6. C The proportions of CD4+ T cells in the liver in the different groups, n = 6. D Dot plots showing CD8+ T cells in the spleen and liver. E The proportions of CD8+ T cells in the spleen in the different groups, n = 6. F The proportions of CD8+ T cells in the liver in the different groups, n = 6. *: P < 0.05, **: P < 0.01, ***: P < 0.001. The differences between groups were calculated using ANOVA. Abbreviations: MSCs, mesenchymal stem cells; sFgl2, soluble fibronectin-like protein 2; WT-MSCs, wild-type MSCs; NC-MSCs, negative control MSCs

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