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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: sFgl2 gene-modified MSCs regulate the differentiation of CD4+ T cells in the treatment of autoimmune hepatitis

Fig. 6

sFgl2-MSCs increased the proportions of Tregs in the spleen and liver in AIH mice and decreased the proportions of Th17 and Th1 cells. A Dot plots showing Tregs among CD4+ T cells in the spleen and liver. B Dot plots showing Th17 cells among CD4+ T cells in the spleen and liver. C Dot plots showing Th17 cells among CD4+ T cells in the spleen and liver. D The proportions of Tregs in the spleen and liver in the different groups, n = 6. E The proportions of Th17 cells in the spleen and liver in the different groups, n ≥ 5. F The proportions of Th1 cells in the spleen and liver in the different groups, n ≥ 5. The differences between groups were calculated using ANOVA. *: P < 0.05, **: P < 0.01, ***: P < 0.001. Abbreviations: MSCs, mesenchymal stem cells; sFgl2, soluble fibronectin-like protein 2; WT-MSCs, wild-type MSCs; NC-MSCs, negative control MSCs

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