Table 1 List of the 157 proteins elements commonly identified in hAMSCs secretome pools 1–4

P62328

Thymosin beta-4

TYB4

5,0

P02795

Metallothionein-2

MT2

6,0

P05387

60S acidic ribosomal protein P2

RLA2

11,7

P99999

Cytochrome c

CYC

11,7

O75368

SH3 domain-binding glutamic acid-rich-like protein

SH3L1

12,8

P09382

Galectin-1

LEG1

14,7

P0DP25

Calmodulin-3

CALM3

16,8

P60660

Myosin light polypeptide 6

MYL6

16,9

P15531

Nucleoside diphosphate kinase A

NDKA

17,1

P62937

Peptidyl-prolyl cis–trans isomerase A

PPIA

18,0

P19105

Myosin regulatory light chain 12A

ML12A

19,8

Q99497

Parkinson disease protein 7

PARK7

19,9

P21291

Cysteine and glycine-rich protein 1

CSRP1

20,6

P55145

Mesencephalic astrocyte-derived neurotrophic factor

MANF

20,7

Q06830

Peroxiredoxin-1

PRDX1

22,1

P37802

Transgelin-2

TAGL2

22,4

Q01995

Transgelin

TAGL

22,6

P80723

Brain acid soluble protein 1

BASP1

22,7

P01033

Metalloproteinase inhibitor 1

TIMP1

23,2

P09211

Glutathione S-transferase P

GSTP1

23,3

P23284

Peptidyl-prolyl cis–trans isomerase B

PPIB

23,7

P16035

Metalloproteinase inhibitor 2

TIMP2

24,4

P09936

Ubiquitin carboxyl-terminal hydrolase isozyme L1

UCHL1

24,8

P62906

60S ribosomal protein L10a

RL10A

24,8

P20618

Proteasome subunit beta type-1

PSB1

26,5

P60174

Triosephosphate isomerase

TPIS

26,7

P48307

Tissue factor pathway inhibitor 2

TFPI2

26,9

P78417

Glutathione S-transferase omega-1

GSTO1

27,5

P52823

Stanniocalcin-1

STC1

27,6

P63104

14–3-3 protein zeta/delta

1433Z

27,7

P61981

14–3-3 protein gamma

1433G

28,3

P25788

Proteasome subunit alpha type-3

PSA3

28,4

P67936

Tropomyosin alpha-4 chain

TPM4

28,5

Q16270

Insulin-like growth factor-binding protein 7

IBP7

29,1

P62258

14–3-3 protein epsilon

1433E

29,2

P28070

Proteasome subunit beta type-4

PSB4

29,2

O00584

Ribonuclease T2

RNT2

29,5

P25786

Proteasome subunit alpha type-1

PSA1

29,5

P47756

F-actin-capping protein subunit beta

CAPZB

31,3

P29966

Myristoylated alanine-rich C-kinase substrate

MARCS

31,5

P17936

Insulin-like growth factor-binding protein 3

IBP3

31,7

P00491

Purine nucleoside phosphorylase

PNPH

32,1

P09486

SPARC

SPRC

34,6

Q12841

Follistatin-related protein 1

FSTL1

35,0

P40926

Malate dehydrogenase, mitochondrial

MDHM

35,5

P08758

Annexin A5

ANXA5

35,9

P04406

Glyceraldehyde-3-phosphate dehydrogenase

G3P

36,0

P40925

Malate dehydrogenase, cytoplasmic

MDHC

36,4

P07195

L-lactate dehydrogenase B chain

LDHB

36,6

P00338

L-lactate dehydrogenase A chain

LDHA

36,7

O43852

Calumenin

CALU

37,1

P37837

Transaldolase

TALDO

37,5

P07858

Cathepsin B

CATB

37,8

Q9UBP4

Dickkopf-related protein 3

DKK3

38,4

P07355

Annexin A2

ANXA2

38,6

P04083

Annexin A1

ANXA1

38,7

Q15293

Reticulocalbin-1

RCN1

38,9

P04075

Fructose-bisphosphate aldolase A

ALDOA

39,4

P60709

Actin, cytoplasmic 1

ACTB

41,7

P36222

Chitinase-3-like protein 1

CH3L1

42,6

P07093

Glia-derived nexin

GDN

44,0

P08727

Keratin, type I cytoskeletal 19

K1C19

44,1

P07339

Cathepsin D

CATD

44,5

P00558

Phosphoglycerate kinase 1

PGK1

44,6

P05121

Plasminogen activator inhibitor 1

PAI1

45,0

P50454

Serpin H1

SERPH

46,4

P06733

Alpha-enolase

ENOA

47,1

Q8NBS9

Thioredoxin domain-containing protein 5

TXND5

47,6

Q15113

Procollagen C-endopeptidase enhancer 1

PCOC1

47,9

Q15084

Protein disulfide-isomerase A6

PDIA6

48,1

P27797

Calreticulin

CALR

48,1

O95967

EGF-containing fibulin-like extracellular matrix protein 2

FBLN4

49,4

P13489

Ribonuclease inhibitor

RINI

49,9

P26641

Elongation factor 1-gamma

EF1G

50,1

P68363

Tubulin alpha-1B chain

TBA1B

50,1

P31150

Rab GDP dissociation inhibitor alpha

GDIA

50,6

P50395

Rab GDP dissociation inhibitor beta

GDIB

50,6

Q01518

Adenylyl cyclase-associated protein 1

CAP1

51,9

P05787

Keratin, type II cytoskeletal 8

K2C8

53,7

P03956

Interstitial collagenase

MMP1

54,0

P09238

Stromelysin-2

MMP10

54,1

P30101

Protein disulfide-isomerase A3

PDIA3

56,7

Q16851

UTP–glucose-1-phosphate uridylyltransferase

UGPA

56,9

P07237

Protein disulfide-isomerase

PDIA1

57,1

P12081

Histidine–tRNA ligase, cytoplasmic

HARS1

57,4

P14618

Pyruvate kinase PKM

KPYM

57,9

P07602

Prosaposin

SAP

58,1

P13645

Keratin, type I cytoskeletal 10

K1C10

58,8

P14314

Glucosidase 2 subunit beta

GLU2B

59,4

P35527

Keratin, type I cytoskeletal 9

K1C9

62,0

P06744

Glucose-6-phosphate isomerase

G6PI

63,1

P14866

Heterogeneous nuclear ribonucleoprotein L

HNRPL

64,1

Q08380

Galectin-3-binding protein

LG3BP

65,3

P35908

Keratin, type II cytoskeletal 2 epidermal

K22E

65,4

P04264

Keratin, type II cytoskeletal 1

K2C1

66,0

P29401

Transketolase

TKT

67,8

P02768

Albumin

ALBU

69,3

P0DMV8

Heat shock 70 kDa protein 1A

HS71A

70,0

P13797

Plastin-3

PLST

70,8

P11142

Heat shock cognate 71 kDa protein

HSP7C

70,9

Q16881

Thioredoxin reductase 1, cytoplasmic

TRXR1

70,9

P11021

Endoplasmic reticulum chaperone BiP

BIP

72,3

P13667

Protein disulfide-isomerase A4

PDIA4

72,9

P08253

72 kDa type IV collagenase

MMP2

73,8

P02545

Prelamin-A/C

LMNA

74,1

Q15582

Transforming growth factor-beta-induced protein ig-h3

BGH3

74,6

P09871

Complement C1s subcomponent

C1S

76,6

P02787

Serotransferrin

TRFE

77,0

P00736

Complement C1r subcomponent

C1R

80,1

O00391

Sulfhydryl oxidase 1

QSOX1

82,5

P08238

Heat shock protein HSP 90-beta

HS90B

83,2

O00469

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

PLOD2

84,6

P06396

Gelsolin

GELS

85,6

Q9Y4K0

Lysyl oxidase homolog 2

LOXL2

86,7

P05556

Integrin beta-1

ITB1

88,4

P55072

Transitional endoplasmic reticulum ATPase

TERA

89,3

P14625

Endoplasmin

ENPL

92,4

Q15063

Periostin

POSTN

93,3

P13639

Elongation factor 2

EF2

95,3

Q14764

Major vault protein

MVP

99,3

P12814

Alpha-actinin-1

ACTN1

103,0

P55786

Puromycin-sensitive aminopeptidase

PSA

103,2

O43707

Alpha-actinin-4

ACTN4

104,8

P10253

Lysosomal alpha-glucosidase

LYAG

105,3

Q9Y6C2

EMILIN-1

EMIL1

106,6

P12109

Collagen alpha-1(VI) chain

CO6A1

108,5

P15144

Aminopeptidase N

AMPN

109,5

P27816

Microtubule-associated protein 4

MAP4

120,9

P18206

Vinculin

VINC

123,7

P08123

Collagen alpha-2(I) chain

CO1A2

129,2

P07996

Thrombospondin-1

TSP1

129,3

P35442

Thrombospondin-2

TSP2

129,9

P02461

Collagen alpha-1(III) chain

CO3A1

138,5

P02452

Collagen alpha-1(I) chain

CO1A1

138,9

Q14112

Nidogen-2

NID2

151,2

P08572

Collagen alpha-2(IV) chain

CO4A2

167,4

P11047

Laminin subunit gamma-1

LAMC1

177,5

Q13219

Pappalysin-1

PAPP1

180,9

P20908

Collagen alpha-1(V) chain

CO5A1

183,4

Q14766

Latent-transforming growth factor beta-binding protein 1

LTBP1

186,7

P01024

Complement C3

CO3

187,0

P46940

Ras GTPase-activating-like protein IQGAP1

IQGA1

189,1

Q14767

Latent-transforming growth factor beta-binding protein 2

LTBP2

194,9

P07942

Laminin subunit beta-1

LAMB1

197,9

P35579

Myosin-9

MYH9

226,4

Q9Y490

Talin-1

TLN1

269,6

P02751

Fibronectin

FINC

272,2

O75369

Filamin-B

FLNB

278,0

P21333

Filamin-A

FLNA

280,6

Q13813

Spectrin alpha chain, non-erythrocytic 1

SPTN1

284,4

Q14315

Filamin-C

FLNC

290,8

P35555

Fibrillin-1

FBN1

312,1

Q99715

Collagen alpha-1(XII) chain

COCA1

332,9

P12111

Collagen alpha-3(VI) chain

CO6A3

343,5

P13611

Versican core protein

CSPG2

372,6

P98160

Basement membrane-specific heparan sulfate proteoglycan core protein

PGBM

468,5

Q07954

Prolow-density lipoprotein receptor-related protein 1

LRP1

504,3

P62328

Thymosin beta-4

TYB4

5,0

P02795

Metallothionein-2

MT2

6,0

P05387

60S acidic ribosomal protein P2

RLA2

11,7

P99999

Cytochrome c

CYC

11,7

O75368

SH3 domain-binding glutamic acid-rich-like protein

SH3L1

12,8

P09382

Galectin-1

LEG1

14,7

P0DP25

Calmodulin-3

CALM3

16,8

P60660

Myosin light polypeptide 6

MYL6

16,9

P15531

Nucleoside diphosphate kinase A

NDKA

17,1

P62937

Peptidyl-prolyl cis–trans isomerase A

PPIA

18,0

P19105

Myosin regulatory light chain 12A

ML12A

19,8

Q99497

Parkinson disease protein 7

PARK7

19,9

P21291

Cysteine and glycine-rich protein 1

CSRP1

20,6

P55145

Mesencephalic astrocyte-derived neurotrophic factor

MANF

20,7

Q06830

Peroxiredoxin-1

PRDX1

22,1

P37802

Transgelin-2

TAGL2

22,4

Q01995

Transgelin

TAGL

22,6

P80723

Brain acid soluble protein 1

BASP1

22,7

P01033

Metalloproteinase inhibitor 1

TIMP1

23,2

P09211

Glutathione S-transferase P

GSTP1

23,3

P23284

Peptidyl-prolyl cis–trans isomerase B

PPIB

23,7

P16035

Metalloproteinase inhibitor 2

TIMP2

24,4

P09936

Ubiquitin carboxyl-terminal hydrolase isozyme L1

UCHL1

24,8

P62906

60S ribosomal protein L10a

RL10A

24,8

P20618

Proteasome subunit beta type-1

PSB1

26,5

P60174

Triosephosphate isomerase

TPIS

26,7

P48307

Tissue factor pathway inhibitor 2

TFPI2

26,9

P78417

Glutathione S-transferase omega-1

GSTO1

27,5

P52823

Stanniocalcin-1

STC1

27,6

P63104

14–3-3 protein zeta/delta

1433Z

27,7

P61981

14–3-3 protein gamma

1433G

28,3

P25788

Proteasome subunit alpha type-3

PSA3

28,4

P67936

Tropomyosin alpha-4 chain

TPM4

28,5

Q16270

Insulin-like growth factor-binding protein 7

IBP7

29,1

P62258

14–3-3 protein epsilon

1433E

29,2

P28070

Proteasome subunit beta type-4

PSB4

29,2

O00584

Ribonuclease T2

RNT2

29,5

P25786

Proteasome subunit alpha type-1

PSA1

29,5

P47756

F-actin-capping protein subunit beta

CAPZB

31,3

P29966

Myristoylated alanine-rich C-kinase substrate

MARCS

31,5

P17936

Insulin-like growth factor-binding protein 3

IBP3

31,7

P00491

Purine nucleoside phosphorylase

PNPH

32,1

P09486

SPARC

SPRC

34,6

Q12841

Follistatin-related protein 1

FSTL1

35,0

P40926

Malate dehydrogenase, mitochondrial

MDHM

35,5

P08758

Annexin A5

ANXA5

35,9

P04406

Glyceraldehyde-3-phosphate dehydrogenase

G3P

36,0

P40925

Malate dehydrogenase, cytoplasmic

MDHC

36,4

P07195

L-lactate dehydrogenase B chain

LDHB

36,6

P00338

L-lactate dehydrogenase A chain

LDHA

36,7

O43852

Calumenin

CALU

37,1

P37837

Transaldolase

TALDO

37,5

P07858

Cathepsin B

CATB

37,8

Q9UBP4

Dickkopf-related protein 3

DKK3

38,4

P07355

Annexin A2

ANXA2

38,6

P04083

Annexin A1

ANXA1

38,7

Q15293

Reticulocalbin-1

RCN1

38,9

P04075

Fructose-bisphosphate aldolase A

ALDOA

39,4

P60709

Actin, cytoplasmic 1

ACTB

41,7

P36222

Chitinase-3-like protein 1

CH3L1

42,6

P07093

Glia-derived nexin

GDN

44,0

P08727

Keratin, type I cytoskeletal 19

K1C19

44,1

P07339

Cathepsin D

CATD

44,5

P00558

Phosphoglycerate kinase 1

PGK1

44,6

P05121

Plasminogen activator inhibitor 1

PAI1

45,0

P50454

Serpin H1

SERPH

46,4

P06733

Alpha-enolase

ENOA

47,1

Q8NBS9

Thioredoxin domain-containing protein 5

TXND5

47,6

Q15113

Procollagen C-endopeptidase enhancer 1

PCOC1

47,9

Q15084

Protein disulfide-isomerase A6

PDIA6

48,1

P27797

Calreticulin

CALR

48,1

O95967

EGF-containing fibulin-like extracellular matrix protein 2

FBLN4

49,4

P13489

Ribonuclease inhibitor

RINI

49,9

P26641

Elongation factor 1-gamma

EF1G

50,1

P68363

Tubulin alpha-1B chain

TBA1B

50,1

P31150

Rab GDP dissociation inhibitor alpha

GDIA

50,6

P50395

Rab GDP dissociation inhibitor beta

GDIB

50,6

Q01518

Adenylyl cyclase-associated protein 1

CAP1

51,9

P05787

Keratin, type II cytoskeletal 8

K2C8

53,7

P03956

Interstitial collagenase

MMP1

54,0

P09238

Stromelysin-2

MMP10

54,1

P30101

Protein disulfide-isomerase A3

PDIA3

56,7

Q16851

UTP–glucose-1-phosphate uridylyltransferase

UGPA

56,9

P07237

Protein disulfide-isomerase

PDIA1

57,1

P12081

Histidine–tRNA ligase, cytoplasmic

HARS1

57,4

P14618

Pyruvate kinase PKM

KPYM

57,9

P07602

Prosaposin

SAP

58,1

P13645

Keratin, type I cytoskeletal 10

K1C10

58,8

P14314

Glucosidase 2 subunit beta

GLU2B

59,4

P35527

Keratin, type I cytoskeletal 9

K1C9

62,0

P06744

Glucose-6-phosphate isomerase

G6PI

63,1

P14866

Heterogeneous nuclear ribonucleoprotein L

HNRPL

64,1

Q08380

Galectin-3-binding protein

LG3BP

65,3

P35908

Keratin, type II cytoskeletal 2 epidermal

K22E

65,4

P04264

Keratin, type II cytoskeletal 1

K2C1

66,0

P29401

Transketolase

TKT

67,8

P02768

Albumin

ALBU

69,3

P0DMV8

Heat shock 70 kDa protein 1A

HS71A

70,0

P13797

Plastin-3

PLST

70,8

P11142

Heat shock cognate 71 kDa protein

HSP7C

70,9

Q16881

Thioredoxin reductase 1, cytoplasmic

TRXR1

70,9

P11021

Endoplasmic reticulum chaperone BiP

BIP

72,3

P13667

Protein disulfide-isomerase A4

PDIA4

72,9

P08253

72 kDa type IV collagenase

MMP2

73,8

P02545

Prelamin-A/C

LMNA

74,1

Q15582

Transforming growth factor-beta-induced protein ig-h3

BGH3

74,6

P09871

Complement C1s subcomponent

C1S

76,6

P02787

Serotransferrin

TRFE

77,0

P00736

Complement C1r subcomponent

C1R

80,1

O00391

Sulfhydryl oxidase 1

QSOX1

82,5

P08238

Heat shock protein HSP 90-beta

HS90B

83,2

O00469

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

PLOD2

84,6

P06396

Gelsolin

GELS

85,6

Q9Y4K0

Lysyl oxidase homolog 2

LOXL2

86,7

P05556

Integrin beta-1

ITB1

88,4

P55072

Transitional endoplasmic reticulum ATPase

TERA

89,3

P14625

Endoplasmin

ENPL

92,4

Q15063

Periostin

POSTN

93,3

P13639

Elongation factor 2

EF2

95,3

Q14764

Major vault protein

MVP

99,3

P12814

Alpha-actinin-1

ACTN1

103,0

P55786

Puromycin-sensitive aminopeptidase

PSA

103,2

O43707

Alpha-actinin-4

ACTN4

104,8

P10253

Lysosomal alpha-glucosidase

LYAG

105,3

Q9Y6C2

EMILIN-1

EMIL1

106,6

P12109

Collagen alpha-1(VI) chain

CO6A1

108,5

P15144

Aminopeptidase N

AMPN

109,5

P27816

Microtubule-associated protein 4

MAP4

120,9

P18206

Vinculin

VINC

123,7

P08123

Collagen alpha-2(I) chain

CO1A2

129,2

P07996

Thrombospondin-1

TSP1

129,3

P35442

Thrombospondin-2

TSP2

129,9

P02461

Collagen alpha-1(III) chain

CO3A1

138,5

P02452

Collagen alpha-1(I) chain

CO1A1

138,9

Q14112

Nidogen-2

NID2

151,2

P08572

Collagen alpha-2(IV) chain

CO4A2

167,4

P11047

Laminin subunit gamma-1

LAMC1

177,5

Q13219

Pappalysin-1

PAPP1

180,9

P20908

Collagen alpha-1(V) chain

CO5A1

183,4

Q14766

Latent-transforming growth factor beta-binding protein 1

LTBP1

186,7

P01024

Complement C3

CO3

187,0

P46940

Ras GTPase-activating-like protein IQGAP1

IQGA1

189,1

Q14767

Latent-transforming growth factor beta-binding protein 2

LTBP2

194,9

P07942

Laminin subunit beta-1

LAMB1

197,9

P35579

Myosin-9

MYH9

226,4

Q9Y490

Talin-1

TLN1

269,6

P02751

Fibronectin

FINC

272,2

O75369

Filamin-B

FLNB

278,0

P21333

Filamin-A

FLNA

280,6

Q13813

Spectrin alpha chain, non-erythrocytic 1

SPTN1

284,4

Q14315

Filamin-C

FLNC

290,8

P35555

Fibrillin-1

FBN1

312,1

Q99715

Collagen alpha-1(XII) chain

COCA1

332,9

P12111

Collagen alpha-3(VI) chain

CO6A3

343,5

P13611

Versican core protein

CSPG2

372,6

P98160

Basement membrane-specific heparan sulfate proteoglycan core protein

PGBM

468,5

Q07954

Prolow-density lipoprotein receptor-related protein 1

LRP1

504,3