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Table 5 List of the top ten clusters significantly enriched among the 78 proteins (Fig. 5) not classified as secreted proteins

From: Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization

#term ID

Term description

Observed gene count

Background gene count

Strength

FDR

Matching proteins in your network (gene name)

CL:11,548

Carbon metabolism, and Starch and sucrose metabolism

13

124

1.42

3.52E-11

TPI1,ENO1,GAA,PKM,TALDO1,MDH2,UGP2,PGK1,ALDOA,LDHB,TKT,MDH1,LDHA

CL:17,048

RHO GTPases Activate WASPs and WAVEs, and actin filament organization

12

105

1.46

7.94E-11

VCL,ACTN4,IQGAP1,ANXA5,TLN1,PLS3,ACTB,FLNA,CAP1,TMSB4X, ACTN1,FLNB

CL:11,549

Carbon metabolism, and Pyruvate metabolism

11

96

1.46

3.22E-10

TPI1,ENO1,PKM,TALDO1,MDH2,PGK1,ALDOA,LDHB,TKT,MDH1,LDHA

CL:11,551

Pentose phosphate pathway, and Glycolysis

9

55

1.61

2.29E-09

TPI1,ENO1,PKM,TALDO1,PGK1,ALDOA,LDHB,TKT,LDHA

CL:17,127

Mixed, incl. profilin binding, and profilin

7

33

1.73

9.01E-08

VCL,ACTN4,IQGAP1,TLN1,ACTB,TMSB4X, ACTN1

CL:17,130

Mixed, incl. profilin binding, and ef-hand, ca insensitive

6

17

1.95

1.27E-07

VCL,ACTN4,TLN1,ACTB,TMSB4X,ACTN1

CL:17,049

RHO GTPases Activate WASPs and WAVEs, and actin filament organization

9

96

1.37

1.28E-07

VCL,ACTN4,IQGAP1,TLN1,PLS3,ACTB,CAP1,TMSB4X,ACTN1

CL:11,554

Glycolysis, and Fructose-1,6-bisphosphatase

6

31

1.69

2.20E-06

TPI1,ENO1,TALDO1,PGK1,ALDOA,TKT

CL:17,150

EF-hand, Ca insensitive, and Vinculin

4

5

2.3

8.11E-06

VCL,ACTN4,TLN1, ACTN1

CL:17,373

Muscle protein, and sarcomere organization

6

68

1.35

0.00012

MYH9,MYL12A,FLNC,TPM4,TAGLN,MYL6