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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Systemically delivered adipose stromal vascular fraction mitigates radiation-induced gastrointestinal syndrome by immunomodulating the inflammatory response through a CD11b+ cell-dependent mechanism

Fig. 2

SVF treatment promotes recruitment and maturation of monocytes in ileum. A Strategy of monocyte gating. Percentage of B CD11b+Ly6C+CCR2+, CD11b+Ly6C+MCHII− (P1), C CD11b+Ly6C−MCHII+CX3Cr1int (P2) and CD11b+Ly6C−MCHII+ CX3Cr1+ (P3) among CD45+ cells from ileal lamina propria of control and at day 1, 3, 7 post-irradiation with or without SVF treatment. The data are represented by mean ± SEM (for each groups n = 6). P values were calculated by ANOVA with Tukey correction; *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group; #p < 0.05; ##p < 0.01; ###p < 0.001 compared with the irradiated group. D Representative immuno co-staining Ly6C (red), CX3CR1 (green) in the ileum at Day 7 post-irradiation with or without SVF treatment. Dapi stained nuclei (blue). Scale bar: 50 µm

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