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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Osteogenic human MSC-derived extracellular vesicles regulate MSC activity and osteogenic differentiation and promote bone regeneration in a rat calvarial defect model

Fig. 2

Analysis of DEPs in proteins (745) common to Osteo- and Naïve-EVs groups. a Venn diagram representing the numbers of unique and overlapping proteins among the common protein in each EV group. b i and ii Volcano plot and Venn diagram showing differentially expressed proteins (p < 0.05) when comparing Osteo-EVs to Naïve-EVs. c Heat map showing the distribution of DEPs among the three donors of each EV group. Values represent protein level quantification (log2). d and e The enriched GO terms (BP, and MF) and REAC pathways for the DEPs in each EV group, respectively, are retrieved from the gene ontology resource

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