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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Grafted human-induced pluripotent stem cells-derived oligodendrocyte progenitor cells combined with human umbilical vein endothelial cells contribute to functional recovery following spinal cord injury

Fig. 2

Oligodendrocytes form Nodes of Ranvier in vitro. a Expression of Tuj1 and GFAP at day 85 (GFP, green; Tuj1, red; GFAP, white). Scale bars, 100 μm. b Different cell types proportion generated on day 75 of differentiation. Data are means ± SEM, ns, no significance; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, One-way ANOVA, N = 3 independent experiments. c–d Immunofluorescence staining of Caspr/MBP and Caspr/Tuj1 at day 75. Nodes of Ranvier (arrowheads) were co-labeled with MBP and Tuj1 (Caspr, red; MBP/Tuj1, white). Scale bars, 25 μm (c), 50 μm (d)

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