Fig. 2

Assessment of glial modulation by 31 kD hESCs following root avulsion and reimplantation. Representative images of (A - B) astroglial and (C – D) microglial reactivity. (E) Quantification of astroglial reactivity. All groups exhibited reduced astrocytic expression. (F) Quantification of microglial reactivity. Observe the increased microgliosis in the group treated with activated hESC (AvR + HFB + Dox + hESC 31 kD) (**p < 0.01). The astroglial and microglial reactivities were assessed using the integrated density of pixels (ipsilateral/contralateral ratio, n = 5 per group). Data are presented as mean ± SEM; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001