Fig. 1

Principal component analysis (PCA) and Screening of DEGs. A. PCA of DEGs between samples of MSCs from young (< 65 years of age) and old (> 65) donors in the GSE39035 dataset. B. PCA of DEGs between samples of MSCs from young (< 65 years of age) and old (> 65) donors in the GSE97311 dataset. C. Heatmap of DEGs in samples of MSCs from young (< 65 years of age) and old (> 65) donors in the GSE39035 dataset. D. Heatmap of DEGs in samples of MSCs from young (< 65 years of age) and old (> 65) donors in the GSE97311 dataset. Red rectangles represent a high level of expression, and blue rectangles represent a low level of expression. Group1 from young (< 65 years of age) and Group2 from old (> 65) donors. E. Venn diagram of intersecting co-expressed upregulated genes (DEGs) from the GSE39035 and GSE97311 datasets. logFC > 1, and adj.P < 0.05. F. Venn diagram of intersecting co-expressed downregulated genes (DEGs) from GSE39035 and GSE97311 datasets. logFC <-1, and adj.P < 0.05