Fig. 2
Macroscopic effect of DPSC-CM against CYP-mediated cytotoxicity in mice. A Experimental design of the mouse model to study CIA progression and the damage-response pathway. B Time course of alopecia and hair regrowth in the mouse model for studying the damage-response pathway. C Representative macroscopic effect images of CIA on day 14 p.d. D Macroscopic analysis of CIA on days 14 and 16 p.d. E Representative macroscopic effect images of post-CIA hair regrowth on day 32 p.d. F Macroscopic analysis of regrowth of secondary recovery (black-pigmented) hair shafts in the nuchal dorsal skin on day 32 p.d. (n = 6 in each group). A–F Days 0–14 p.d., n = 18 in each group; days 15–16 p.d., n = 12 in each group; and days 17–32 p.d., n = 6 in each group. Data are presented as mean ± SEM. ***P < 0.001. QD, quaque die