Fig. 2
From: Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy
Generation of NSCs, MGE and interneurons from human-induced pluripotent stem cells. The top panel represents neural stem cells on day 10 positive for NESTIN (green) and SOX 2 (red), and the merged image demonstrates cells positive for both NESTIN and SOX2 (orange). The middle panel represents medial ganglionic eminence (MGE) cells on day 25 positive for NKX2.1 (green) and DAPI (blue), and the merged image demonstrates cells positive for NKX2.1 and DAPI. The lower panel represents GABAergic interneurons on day 45, positive for β-III tubulin (green) and GABA (red), and the merged image demonstrates cells positive for both β-III tubulin and GABA (orange)