Figure 6

Summary of the multiplex cytokine analysis of bone marrow mononuclear cells (BMMNCs) compared to ixmyelocel-T CD90⁺ and CD14⁺Auto populations. Cells were cultured for approximately 24 hours in multiwell plates and cytokine levels were measured in comparison to blank medium negative controls. CD90⁺ and CD14⁺Auto⁺ populations were sorted using fluorescence-activated cell sorting to high purity prior to culture. Non-paired data from two or more independent donors assayed in replicate are expressed as the mean cytokine concentration ± standard error in pg/ml. IL-1ra, IL-1 receptor antagonist; HGF, hepatocyte growth factor; MIP, macrophage inflammatory protein; VEGF, vascular endothelial growth factor.