Expression of migration-related genes is progressively upregulated in murine Lineage-Sca-1+c-Kit+ population from the fetal to adult stages of development

Table 3 Folding expression of chemokines and receptors in LSK across different locations and stages of development

Gene	FL14.5	FL17.5	FBM17.5	Adult BM
Chemokine (C-C motif) Ligands
Ccl4	0.02	0.17	0.18	1
Ccl5	0.05	0.2	0.19	1
Ccl6	0.02	0.13	0.08	1
Ccl9	0.09	0.24	0.18	1
Chemokine (C-X-C motif) Ligands
Cxcl2	0.03	0.24	0.17	1
Pf4	0.47	0.31	1.72	1
Chemokine (C-C motif) Receptors
Cxcr4	0.31	0.38	0.76	1
Other Chemokines and Related Genes
Cmtm3	0.72	0.93	0.73	1
Cmtm6	0.28	0.22	0.45	1
Hif1a	0.5	1.07	0.75	1
Il16	0.42	0.37	0.82	1
Il18	0.04	0.21	0.57	1
Mmp2	0.07	0.2	0.27	1
Nfkb1	0.48	0.82	0.84	1
Tlr4	0.01	0.11	0.23	1
Tnfrsf1a	0.4	0.45	0.71	1
Tnfsf14	0.18	0.31	0.43	1
Housekeeping Gene
Hprt1	0.48	0.81	0.63	1

This table demonstrates fold change values for samples in which gene expression was detected at all the points of study, compared to gene expression in adult bone marrow. Adult BM, four-week old adult bone marrow; FBM17.5, fetal bone marrow at Day 17.5 of gestation; FL14.5, fetal liver at Day 14.5 of gestation; FL17.5, fetal liver at Day 17.5 of gestation; LSK, Lineage^- Sca-1⁺ c-Kit⁺.

ISSN: 1757-6512