Figure 3

Bcl-2 overexpression decreases cell death. Representative pictures of neuroepithelial stem cell (NESC) grafts in cross-sections of rat colon in the (A) control group and (B) Bcl-2 group at 1 week post transplantation. 4',6-Diamidino-2-phenylindole-positive NESCs are shown in blue. Terminal uridine nick end-labeling (TUNEL) immunoreactivity is indicated in green. Transplanted NESCs that are TUNEL-positive are indicated by arrows. LM, longitudinal muscle; CM, circular muscle. Scale bar = 200 μm. (C) Quantitative analysis of the number of grafted NESCs that are TUNEL-positive in two groups. Data expressed as mean ± standard error of the mean; n = 6 for each group; *P < 0.05 versus control group.