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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade

Figure 1

Expression of heme oxygenase-1 (HO-1), with time, on adipogenesis. (A) Pictures of lipid droplets of a representative experiment at days 3, 5, 10, and 14. Adipogenesis was measured as the relative absorbance of Oil Red O as described in Materials and methods (mean ± SD, *P < 0.05 vs control). (B) Western blot of HO-1 and actin in mesenchymal stem cell (MSC)-derived adipocytes from day 0 to day 14. Representative immunoblots and densitometry analysis are shown. Data are expressed as means ± SD; n = 4; *P < 0.05. (C) Lactic dehydrogenate (LDH) assay done to study the cytotoxicity at increasing concentrations of cobalt-protoporphyrin IX (CoPP). Data are expressed as means ± SD; n = 8, *P < 0.05 vs MSC control, **P < 0.05 vs adipocytes control.

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Stem Cell Research & Therapy

ISSN: 1757-6512