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Table 1 Representative preclinical animal studies using adipose-derived stromal/stem cells and stromal vascular fraction cells

From: Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells

Tissue type Defect Species References
Adipose/soft tissue Fat pad generation Murine, rat, ovine [5160]
  Lipodystrophy Murine [48, 61]
  Burn/radiation trauma Murine [6264]
Bone Critical sized defect   
     Craniofacial Murine, rat [65, 66]
     Long bone Murine [67]
  Spinal fusion Rat [68, 69]
Cardiac Myocardial infarction Murine, rat [42, 43, 70, 71]
Central nervous system Vascular injury/stroke Murine, rat [44, 46, 72]
  Spinal cord trauma Rat [47]
  Multiple sclerosis Murine [33]
Gastrointestinal tract Crohn's disease/inflammatory bowel syndrome Murine [73]
Hematopoiesis Bone marrow transplantation Murine [74, 75]
Joint Osteoarthritis Canine, caprine, equine [7679]
Liver Acute toxicity/regeneration Murine [8088]
Pancreas Type 1 diabetes mellitus Murine, rat [48, 89, 90]
Renal Acute ischemia Rat (JMG, unpublished)
Skin Wounds, burns Murine, porcine [62, 64, 91]
Tendon Tendonitis Equine [92]
Urinary bladder Incontinence Rat [93]
Vascular Hind limb ischemia Murine, rat [36, 41, 45]