Figure 5
Amniotic fluid stem cells (AFS)-derived cells migrate to other organs. The 105 AFSs derived from a Rosa26 donor were injected into cleared fat pads of 3-week-old recipient mice and analyzed 14 weeks later. X-Gal-stained whole mounts demonstrate the presence of LacZ+ cells in several organs. Tissue sections show the localization of AFS-derived LacZ+ cells between hepatocytes, adjacent to airway epithelial cells, and in the mucosa of the gastrointestinal tract. Scale bar for whole mounts is 500 μm, and for sections, 50 μm, (Blue) X-Gal stain and (Pink) Nuclear fast red staining.