Figure 6

PGE2, IL-10 and TGF-β1 expression on MSCs co-cultured with Th1 and Th17 cells. A) PGE2 was quantified in the supernatants of MSCs co-cultured in the presence or absence of Th1 and Th17 cells. B) IL-10 and TGF-β1 expression was quantified in the supernatants of MSCs cultured in contact with Th1 and Th17 cells at different stages of the differentiation process (Day 0 and 4) ** = P <0.01, * = P <0.05, comparing to MSCs as the control group. All the values represent means ± SED of three independent experiments. MSCs, mesenchymal stem cells; PGE2, prostaglandin E2; TGF-β1, transforming growth factor β; Th, T helper.