Figure 5

Changes in gene expression after epithelial transdifferentiation of subpopulations A, B, C, and PLCSC populations. Comparative qPCR was performed for epithelial progenitor genes (a, b, c, d, HES1, FRZ1, DCT, SOD2, ABCG2, CDH1, and KRT19) and terminally differentiated epithelial genes (e, f, g, h DSG3, KRT3, KRT12, KRT24). All fold changes are expressed relative to control gene 18S. Inset images show data on a reduced scale. Values are represented as mean ± SD. The experiment was repeated in triplicate, each with n = 3. Statistical significance is represented as *P ≤ 0.01, **P ≤ 0.001, ***P ≤ 0.0001.