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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: MicroRNA-20b and ERK1/2 pathway independently regulate the expression of tissue factor in hematopoietic and trophoblastic differentiation of human embryonic stem cells

Figure 6

Erk1/2 signaling pathway and miR-20b regulate tissue factor expression in trophoblastic and hematopoietic differentiation of human embryonic stem cells. Granulocyte–macrophage (G-M) cells and trophoblasts were treated with both miR-20b inhibitor and Erk1/2-specific inhibitor U0126, simultaneously for 48 hours before harvesting for quantitative real-time polymerase chain reaction to measure the mRNA levels of PU.1, CDX2, and tissue factor (TF). Data reported as the mean ± standard error of the percentage of the mRNA levels of the corresponding gene in cells without treatment. *P <0.05, **P <0.01.

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