Figure 6

MRI in vivo cell tracking and histological evaluation of synovial joint. A) Signal profiles, B) corresponding coronal FLASH (day 3) and GEFI (day 7) MRI scans, C) H & E sections of synovial joint highlighting location of SiMAG labelled cells by D i) CM- DIL (red) and DAPI (blue). Fluorescent analysis and D ii) corresponding Prussian blue stain for i) group 1 (+ mMSCS, + SiMAG; three days, N = 6), ii) group 2 (+ mMSCS, + SiMAG; seven days, N = 5), iii) group 3 (+ mMSCS, - SiMAG; three days, N = 6) and iv) group 6 (− fmMSCS, - SiMAG; seven days, N = 5).T, tibia; F, Femur; M, meniscus. Bars = 100 μm. FLASH, fast low angle shot; GEFI, gradient-echo fast imaging; mMSCs, murine mesenchymal stem cells; MRI, magnetic resonance imaging.