Figure 2
From: Ixmyelocel-T, an expanded multicellular therapy, contains a unique population of M2-like macrophages
The expansion process used to produce ixmyelocel-T results in an anti-inflammatory cytokine profile. (A) IL-10, (B) IL-r1a, (C) TNFα, (D) IL-12 were quantified in BMMNCs and ixmyelocel-T supernatants treated with and without 0.1 μg/mL LPS (n = 5–11). Values are presented as mean ± SEM relative to control, *P <0.01, **P <0.001 vs BMMNC + LPS. #P <0.01, ##P <0.001 vs IXT + LPS. &P <0.01 vs BMMNC -LPS. LPS, lipopolysaccharide; SEM = standard error of the mean.